Dr. Draper and I had discussed me going on an antidepressant, but I was not in favor of adding another drug to the mix and I wanted to see how I did without it. And since things had been going a little better, I thought I could manage on my own just fine with out it.

Then things took a turns for the worse and the attacks started coming frequently and I was crying all day long. Again I began having irrational thoughts that the baby was harmed and that I was a terrible mother. There were days when I couldn't even get out of bed. Then on a Sunday afternoon I was reading in Parents magazine (I loathe that magazine, BTW) and there was an article about prenatal depression. It talked about how the placenta can actually be damaged if the mother is depressed. There were other things mentioned in teh article that scared me beyond belief, so I decided to try the Zoloft.

The doctor had given me a sample pack at a previous appointment and I had it on hand, so that evening I took my first pill. I was aware that it would take about two weeks to work so I wasn't expecting a quick fix. But I also wasn't expecting that I would experience every side effect listed on the label.

The next day was pure hell. I was dizzy, I threw up a lot, my mouth dried up, I shook like a leaf, I was more anxious than normal, and my heart rate was accelerated. I decided to give it one more day so I took another dose Monday evening. Tuesday was even wrose, if you can believe that. I could not function at all and Brandi came over to babysit me during the day while Cody was gone.

I called my mom that afternoon (she happens to be a PharmD) and asked her if what I was feeling was normal. She went down the list of drugs I was on and said that Trazodone is actually an antidepressant in itself and I was taking 100-150 mg a day, so I could actually be overdosing when combining that with the Zoloft. I decided the side effects were worse than the depression and anxiety so I decided to throw the pills away.

That evening Brandi, her little boy, Ethan, and I went to get dinner and then to see the development on our new house. It was all but done and we walked through it and sat in the empty living room and talked. We would be closing in one week and I tried to feel happy about it, but I couldn't get past how awful I was feeling at the moment. I was trying to distract myself from my misery but it wasn't working.

We drove home, but on the way there I noticed I was breathing very hard and my heart rate had accelerated even more. Brandi helped me back into our apartment and I sat down on the couch. Cody was home by this time and Brandi told him what had happened on the way home. It was like all of the ill side effects I had experienced were now ten fold. I ran to the bathroom and started throwing up again, then I laid down on the bathroom floor and had what I thought was a heart attack. My chest hurt beyond words and I could not breathe.

Cody paged my doctor and when he called back he said to get me up to the hospital for an EKG. What I was experiencing was not normal. On the way out the door I grabbed my Ativan and Trazodone and downed a few pills in the car. Brandi was so sweet to stay at our apartment with Ethan. By the time we made the twenty minute drive to the hospital, I had calmed down immensely and and I was in a state of euphoria. The EKG came back normal and they chalked it up to a massive panic attack. Who knows what had really happened though. We drove back home and I crashed very hard when I hit the pillow.

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In some cases of depression, a patient is able to be successfully treated by seeing a therapist. In these relatively mild cases, the patient is suffering through some conflict or problem and just needs somebody with whom to discuss these problems. After weeks, months, or sometimes, even years of doing this, the patient is able to get past his depression and get on with his life. Again, these are in the more mild cases. However, in some cases where the patient is severely depressed and no amount of therapy seems to be doing any good, the only alternative left is drug therapy. In these cases, what drugs are used? Which ones are most common? Are some stronger than others?
We’ll explore these questions and others in this article.Drugs that are used to treat depression are generally called antidepressants. This, however, is a very general description and each antidepressant works differently and is used for different reasons depending on the type and severity of the depression. It is important to understand that before any drug is given for depression all other options must be explored first. Antidepressants are very strong and have definite side effects, some of which are not very pleasant.
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The most common drugs today for treating depression are called SSRI drugs. SSRI stands for selective serotonin reuptake inhibitors. To understand why these drugs are given, it is important to first understand what is taking place in a person’s brain who happens to be suffering from depression, at least in cases where it is determined that the depression is being caused by a chemical imbalance.In layman’s terms, a person who is depressed is suffering because the neurotransmitters in their brain are not acting properly. These transmitters are supposed to transmit certain levels of noradrenaline and serotonin. When these levels are too low, what happens is that the person exhibits symptoms that we call depression. In order to combat these low levels, these SSRI drugs are given to increase the levels of noradrenaline and serotonin in the brain. Again, this is in layman’s terms and the actual process is a lot more complicated. A trained medical professional must try to determine accurately how low these levels are and by doing this, how much drug needs to be administered. This is not an easy thing to do.The common SSRI drugs that are given today are Prozac, Zoloft, Paxil, Celexa, Lexapro, Effexor and Remeron. These are the brand names for the following generic drugs, fluoxetine, sertraline, paroxetine, fluvoxamine, citalopram, escitalopram, venlafaxine, nefazodone, mirtazapine. The difference between each of these drugs is beyond the scope of this article.
Each one, however, works in a slightly different way and is prescribed based on the severity of the depression. This is not an exact science and sometimes one medication doesn’t work or stops working and another one has to be prescribed.As with any drug, there potential side effects with SSRI drugs. The most common side effects are nausea, insomnia, anxiety, nervousness, no appetite, impotence, headaches and a number of others. How severe the side effect varies from patient to patient. Of course, the worst side effect of any of these drugs is simply that it doesn’t work.
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A panic attack is a sudden episode of intense fear that develops for no apparent reason and that triggers severe physical reactions. Panic attacks can be very frightening. When panic attacks occur, you might think youre losing control, having a heart attack or even dying.
You may have only one or two panic attacks in your lifetime. But if you have panic attacks frequently, it could mean that you have panic disorder, a type of chronic anxiety disorder.
Panic attacks were once dismissed as nerves or stress, but theyre now recognized as a real medical condition. Although panic attacks can significantly affect your quality of life, treatment — including medications, psychotherapy and relaxation techniques to help prevent or control panic attacks — is very effective.

Signs and symptoms
Panic attack symptoms can make your heart pound and cause you to feel short of breath, dizzy, nauseated and flushed. Because panic attack symptoms can resemble life-threatening conditions, its important to seek an accurate diagnosis and treatment.
Panic attack symptoms can include:
* Rapid heart rate
* Sweating
* Trembling
* Shortness of breath
* Hyperventilation
* Chills
* Hot flashes
* Nausea
* Abdominal cramping
* Chest pain
* Headache
* Dizziness
* Faintness
* Tightness in your throat
* Trouble swallowing
* A sense of impending death
You may have a few or many of these panic attack symptoms. Panic attacks typically begin suddenly, without warning. Panic attack symptoms usually peak within 10 minutes and last about half an hour. But panic attacks have many variations. They may last hours or, on rare occasions, up to a day. You may feel fatigued and worn out after a panic attack subsides. One of the worst things about panic attacks is the intense fear that youll have another panic attack.
If you have frequent panic attacks, you may have a condition called panic disorder. Panic attacks can greatly interfere with your life — and perhaps even endanger you or others.
Panic attacks can strike at almost any time without warning — when youre driving the school car pool, at the mall, sound asleep or in the middle of a business meeting. And you may fear having a panic attack so much that you avoid situations where they may occur. You may even be unable to leave your home (agoraphobia), because no place feels safe.
Causes
Its not known what causes panic attacks or panic disorder. Things that may play a role include:
* Genetics
* Stress
* Certain changes in the way parts of your brain function
Some research suggests that your bodys natural fight-or-flight response to danger is involved in panic attacks. For example, if a grizzly bear came after you, your body would react instinctively. Your heart rate and breathing would speed up as your body prepared itself for a life-threatening situation. Many of the same reactions occur in a panic attack. But its not known why a panic attack occurs when theres no obvious danger present.
Treatment
Treatment for panic attacks and panic disorder is very effective. The goal of treatment is to eliminate all of your panic attack symptoms. With effective treatment, most people are eventually able to resume everyday activities. The main treatment options for panic attacks are medications and psychotherapy. Both are equally effective.

Medications
Medications can help reduce symptoms associated with panic attacks, as well as depression if thats an issue for you. Several types of medication have been shown effective in managing symptoms of panic attacks, including:
* SSRIs. These medications are in the class of antidepressants called selective serotonin reuptake inhibitors. Because these medications are generally safe and have a low risk of causing serious side effects, SSRIs are typically recommended as the first choice in medication options to treat panic attacks. They include citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Prozac Weekly), paroxetine (Paxil, Paxil CR) and sertraline (Zoloft).
* SNRIs. These medications are in the class of antidepressants called serotonin and norepinephrine reuptake inhibitors. They include duloxetine and venlafaxine (Effexor, Effexor XR).
* TCAs. These medications are in the class of antidepressants called tricyclic antidepressants. While effective, they pose a risk of serious side effects, including heart and blood sugar problems.
* Benzodiazpines. These medications are mild sedatives. They belong to the group of medicines called central nervous system (CNS) depressants. Benzodiazepines may be habit-forming (causing mental or physical dependence), especially when taken for a long time or in high doses.
* MAOIs. These medications are in the class of antidepressants called monoamine oxidase inhibitors. Because they can cause life-threatening side effects and require strict dietary restrictions, theyre not commonly prescribed.
If one medication doesnt work well for you, your doctor may recommend switching to another or combining certain medications to boost their effectiveness. Keep in mind that it can take several weeks after first starting a medication to notice an improvement in your symptoms. All medications have a risk of side effects, and some may not be recommended in certain situations, such as pregnancy. Be sure to talk to your doctor about the possible side effects and risks.
Psychotherapy
Psychotherapy, also called counseling or talk therapy, can help you understand panic attacks and panic disorder and how to cope with them. The main type of psychotherapy used to treat panic attacks and panic disorder is cognitive behavioral therapy. Some experts recommend that you have therapy with a psychiatrist or psychologist with experience in treating panic disorder.
Cognitive behavioral therapy can help you change thinking (cognitive) patterns that trigger your fears and panic attacks. It can also help you change the way you react (behave) to anxious or fearful situations. During therapy sessions, you learn to recognize things that trigger your panic attacks or make them worse, such as specific thoughts or situations. You also learn ways to cope with the anxiety and physical symptoms associated with panic attacks. These may include breathing and relaxation techniques.
In addition, working carefully with your therapist, you may re-create the symptoms of panic attacks in the safety of his or her office. This is an important step because it can help you learn to control and master the symptoms so that they dont continue to be a source of intense fear. Doing this can also help you overcome fear of certain situations that you may avoid, such as crowded malls or driving.
Your therapist may suggest weekly meetings when you first start treatment. You may start to see improvements in panic attack symptoms within several weeks, and often symptoms go away within several months.
As your symptoms improve, maintenance therapy with visits once a month can help ensure that your panic attacks remain under control. Eventually you can stop therapy when your symptoms completely go away, which may be a year or so. However, panic attack symptoms do sometimes come back. Seek prompt treatment if they do, and make sure that youre managing any stressful life situations.

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This registry is a place to share positive or negative side effects of using Zoloft. If you directly experienced a side effect while using Zoloft, then we encourage you to enter it here. Please note that entries here are the experiences of individual users, and in no way means that you or anyone else will experience the same side effect, since the same medication affects people in different ways. Please always contact your physician.

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Zoloft is an FDA approved medication used to treat a variety of disorders which range from depression, and social anxiety to post-traumatic stress disorder and obsessive compulsive disorder. Recommended for adults over the age of 18, Zoloft has been helping people for more than 15 years.
If you want to gain access to the medication that is best suited for you, please feel free to explore your options here on this site. You will find a list of the most trusted and used online pharmacies. Do not hesitate. Get your life back in control today with Zoloft.

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I agree. Zoloft didn't cause his family problems, but his violence and sudden agitation while on the drug leave something to be desired. I grant to you that Pfizer did not report homicide as a post-marketing side effect as a result of the case.
Other Events Observed During the Post marketing Evaluation of ZOLOFT–Reports of adverse events temporally associated with ZOLOFT that have been received since market introduction, that are not listed above and that may have no causal relationship with the drug, include the following: acute renal failure, anaphylactoid reaction, angioedema, blindness, optic neuritis, cataract, increased coagulation times, bradycardia, AV block, atrial arrhythmias, QTinterval prolongation, ventricular tachycardia (including torsade de pointes-type arrhythmias), hypothyroidism, agranulocytosis, aplastic anemia and pancytopenia, leukopenia, thrombocytopenia, lupus-like syndrome, serum sickness, hyperglycemia, galactorrhea, hyperprolactinemia, neuroleptic malignant syndrome-like events, extrapyramidal symptoms, oculogyric crisis, serotonin syndrome, psychosis, pulmonary hypertension, severe skin reactions, which potentially can be fatal, such as Stevens-Johnson syndrome, vasculitis, photosensitivity and other severe cutaneous disorders, rare reports of pancreatitis, and liver events—clinical features (which in the majority of cases appeared to be reversible with discontinuation of ZOLOFT) occurring in one or more patients include: elevated enzymes, increased bilirubin, hepatomegaly, hepatitis, jaundice, abdominal pain, vomiting, liver failure and death.
(Download uspi_zoloft.

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Medications Side Effects Blog Archive Zoloft: Remedy Common uses This medicine is a selective serotonin reuptake inhibitor (SSRI) used to treat depression, panic disorder, obsessive-compulsive disorder (OCD), post-traumatic stress disorder (PTSD), social anxiety disorder (social phobia), and a severe form of premenstrual syndrome called premenstrual dysphoric disorder (PMDD). This medicine works by helping to restore the balance of certain natural substances in the brain known as neurotransmitters. This medicine works on the neurotransmitter serotonin. This medicine may be used to treat other conditions as determined by your doctor. Before using Do not take this medicine if you are also taking pimozide, weight loss medicines such as fenfluramine or sibutramine, cyproheptadine, dextromethorphan, tryptophan, terfenadine, astemizole, pimozide, st. Johns wort, or tramadol. Do not take this medicine with, or within days of taking, a monoamine oxidase inhibitor (maoi). Maois include furazolidone, isocarboxazid, linezolid, moclobemide, phenelzine, procarbazine, selegiline, and tranylcypromine. If you are currently taking any of the medicines mentioned above, tell your doctor or pharmacist before starting sertraline. Additional monitoring of your dose or condition may be needed if you are taking aripiprazole, clozapine, linezolid, lithium, metoclopramide, nonsteroidal anti-inflammatory medicines such as ibuprofen or naproxen, tricyclic anti-depressants (e.g., amitriptyline), other ssri anti-depressants such as citalopram or fluvoxamine, nefazodone, venlafaxine, migraine medicines (e.g., sumatriptan), carbamazepine, risperidone, phenothiazines medicines such as thioridazine, or trazodone. Inform your doctor of any other medical conditions including liver disease, seizures, any allergies, pregnancy, or breast-feeding. Contact your doctor or pharmacist if you have any questions or concerns about taking this medicine. Directions Follow the directions for using this medicine provided by your doctor. Try to you take your dosage at the same time each day, either in the morning or in the evening. Store this medicine at room temperature at 77 degrees f (25 degrees C) away from light and moisture. Brief storage between 5 and 86 degrees f (15 and 30 degrees C) is permitted. Continue to take this medicine even if you feel better. If you miss a dose of this medicine, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once. Cautions Do not take this medicine if you have had an allergic reaction to it or are allergic to any ingredient in this product. Several weeks may pass before this medicine reaches its full effect. Do not stop taking this medicine without checking with your doctor. Additional monitoring of your condition is recommended at the start of treatment with this medicine and whenever a change to your dose is made. If you experience anxiety, agitation, panic attacks, difficulty sleeping, irritability, hostility, impulsive feelings, severe restlessness, or worsening of depression contact your doctor as soon as possible. These may be signs that your condition is worsening or that your treatment with this medicine should be evaluated. If you are a parent or caregiver of a patient that is taking this medicine, it is important for you to watch for these symptoms. Contact the doctor as soon as possible if any of these symptoms occur. Contact your doctor for more information. This medicine may cause drowsiness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to this medicine. Using this medicine alone, with other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks. This medicine will add to the effects of alcohol and other depressants. Ask your pharmacist if you have questions about which medicines are depressants. Before you begin taking any new medicine, either prescription or over-the-counter, check with your doctor or pharmacist. This includes any medicines that cause drowsiness. Check the labels on all your medicines for drowsiness causing ingredients. Ask your pharmacist if you are unsure which products may cause drowsiness. Taking other medicines that cause drowsiness with this medicine may increase the drowsiness effect. Caution is advised when using this medicine in the elderly since they may be more sensitive to the effects of it, including a decrease in sodium levels in the blood. This is especially important if they are also taking water pills or diuretics. Caution is advised when using this medicine in children because they may be more sensitive to the effects of this medicine. It is important to monitor weight and growth in children who are taking this medicine. For women: if you plan on becoming pregnant, discuss with your doctor the benefits and risks of using this medicine during pregnancy, especially during the third trimester. It is unknown if this medicine is excreted in breast milk. If you are or will be breast-feeding while you are using this medicine, check with your doctor or pharmacist to discuss the risks to your baby. Possible side effects Side effects that may occur while taking this medicine include nausea, dry mouth, increased sweating, drowsiness, diarrhea, upset stomach, or trouble sleeping. If they continue or are bothersome, check with your doctor. Check with your doctor as soon as possible if you experience uncontrollable shaking (tremor), loss of appetite, unusual weight loss, decreased interest in sex, or decreased sexual ability. Contact your doctor immediately if you experience unusual or rapid weight gain, unusual or severe mental or mood changes, seizures, thoughts of hurting yourself, or worsening of depression. Males: in the unlikely event you experience a painful or prolonged erection, seek immediate medical attention or permanent problems could occur. An allergic reaction to this medicine is unlikely but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include rash, itching, swelling, dizziness, or trouble breathing. If you notice other effects not listed above, contact your doctor, nurse, or pharmacist. If you take too much If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include increased heartbeat, severe dizziness, severe drowsiness, prolonged vomiting, agitation, and tremor. Additional information Do not share this medicine with others for whom it was not prescribed. Do not use this medicine for other health conditions. Keep this medicine out of the reach of children and pets. If using this medicine for an extended period of time, obtain refills before your supply runs out. Drug interactions Drug interactions can result in unwanted side effects or prevent a medicine from doing its job. Some medicines or medical conditions may interact with this medicine. Inform your doctor or pharmacist of all prescription and over-the-counter medicine that you are taking.

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The US Supreme Court has declined to hear an appeal from a South Carolina teenager who was sentenced to 30 years in prison for killing his grandparents with a shotgun when he was 12 years old, The New York Times reports. Without comment, the justices refused to review the sentence imposed on Christopher Pittman, whose case attracted wide attention not only because of his age and the sentence he received, but because his lawyers blamed Zoloft, the Pfizer antidepressant, for his violent behavior.
The pill wasn’t the central issue, though, in the appeal. In a brief submitted to the court, attorneys from the University of Texas law school argued that the 30-year sentence violates Pittman’s Eighth Amendment protection. The lengthy sentence is “unconstitutionally disproportionate as applied to a 12-year-old child,” they wrote (Heres the brief). The South Carolina Supreme Court ruled last June that the boy’s trial had been fair and the punishment was just.
The Zoloft defense was hotly debated at the time of the February 2005 trial. Shortly before the killings in November 2001, the 12-year-old had been prescribed Zoloft. His parents had taken him to Chester County, S.C., to live with his grandparents, Joe and Joy Pittman, because he was having trouble at home in Florida, the Times notes.

On the day of the killings, Christopher allegedly assaulted a second-grader on a school bus. Later that day, he misbehaved at choir practice. That night, his grandparents confined him to his room and warned him that he would be paddled if he came out. Christopher did come out, and his grandfather was true to his word, according to the newspaper.
Christopher waited for his grandparents to go to bed, then loaded a shotgun, entered their bedroom and shot them to death in their bed. He then lit several candles and positioned them in an apparent attempt to burn the house down, court records recounted. Then he took some money, weapons and his dog and drove off in his grandparents’ car, the Times writes.
The next morning, the paper adds, two hunters found him wandering in the woods. He told them that he had been kidnapped by a black man who had slain his parents and set their house ablaze, but he had been able to escape. The hunters, who were members of the Corinth Fire Department, took him to a fire station and alerted the police. As the police searched for a black suspect, examinations of the crime scene and the vehicle that Christopher had taken turned suspicion toward him, the Times continues. After being told his Miranda rights, he confessed and was convicted of murder and arson on Feb. 15, 2005.
Afterward, a juror said the jury had agreed that Zoloft might have affected Christopher’s behavior, but not enough to impel him to kill. Pfizer called the case “tragic,” but said, “Zoloft didn’t cause his problems, nor did the medication drive him to commit murder.

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